|
T16960 |
Sultiame
|
|
Others
,
Carbonic Anhydrase
|
|
Sultiame is an inhibitor of carbonic anhydrase. |
|
T0515 |
Tioxolone
|
|
Carbonic Anhydrase
|
|
Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor. |
|
T8827 |
EMAC10101d
|
|
Carbonic Anhydrase
|
|
compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an inhibitory activity in the low nanomolar range. |
|
T4321 |
Indisulam
|
E 7070 |
CDK
,
Carbonic Anhydrase
|
|
Indisulam (E 7070) is a carbonic anhydrase inibitor and Antitumor CDK inhibitor. Indisulam targets the G1 phase of the cell cycle by depleting cyclin E. inducing p53 and p21, and inhibiting CDK2, causing a blockade in th... |
|
T0782 |
Benzthiazide
|
Aquatag,Lemazide,Dihydrex |
Carbonic Anhydrase
|
|
Benzthiazide (Lemazide) is used in the therapy of edema and hypertension. Like other thiazides, benzthiazide accelerates water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted ... |
|
T2187 |
Orthanilamide
|
O-Aminobenzenesulfonamide,Benzenesulfonamide,O-Sulfanilamide |
Carbonic Anhydrase
,
Autophagy
|
|
Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline. |
|
T6781 |
Benzenesulfonamide
|
Benzenesulphonamide,Phenyl sulfonamide,Benzosulfonamide |
Carbonic Anhydrase
|
|
Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases. |
|
T6469 |
Dichlorphenamide
|
Diclofenamide,Daranide,Antidrasi |
Carbonic Anhydrase
|
|
Dichlorphenamide (Diclofenamide) is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma. |
|
T6581 |
Methyclothiazide
|
Duretic,Enduron,Aquatensen |
Others
,
Carbonic Anhydrase
|
|
Methyclothiazide (Aquatensen) is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including heart disease. |
|
T36758 |
CAIX Inhibitor S4
|
S4 |
Carbonic Anhydrase
|
|
CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively. The Kis for CA II and CA I are 546 and 5600 nM. |
|
T0142 |
Brinzolamide
|
AL-4862 |
Carbonic Anhydrase
|
|
Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor. |
|
T5012 |
Ethoxzolamide
|
PNU-4191,Redupresin,L-643786 |
Antibacterial
,
Carbonic Anhydrase
|
|
Ethoxzolamide (L-643786) is a carbonic anhydrase inhibitor. |
|
T21294 |
Polmacoxib
|
CG-100649,CG100649,CG 100649 |
COX
,
Carbonic Anhydrase
|
|
Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through... |
|
T23782 |
Benzolamide
|
CL-11366,W 1803,CL 11366,CL11366,W-1803 |
Carbonic Anhydrase
|
|
Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons. |
|
T0106 |
Methazolamide
|
L584601,CL 8490 |
Carbonic Anhydrase
|
|
Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma. |
|
T2017 |
U-104
|
NSC-213841,MST-104 |
Carbonic Anhydrase
|
|
U-104 (NSC-213841) is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM). |
|
T0267 |
Zonisamide
|
AD 810,CI 912 |
Calcium Channel
,
Sodium Channel
,
Carbonic Anhydrase
|
|
Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydrase although this is not one of the main mechanisms... |
|
T6503 |
Fluorometholone Acetate
|
NSC 47438,Flarex,Eflone,Oxylone acetate |
Glucocorticoid Receptor
,
Carbonic Anhydrase
|
|
Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye. |
|
T0675 |
Topiramate
|
RWJ 17021,McN 4853 |
Potassium Channel
,
Calcium Channel
,
GABA Receptor
,
Sodium Channel
,
GluR
,
Carbonic Anhydrase
,
iGluR
|
|
Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepatic injury and largely when used in combination ... |
|
T2134 |
Dorzolamide hydrochloride
|
MK507 hydrochloride,L671152 hydrochloride,MK-507 (L-671152) HCl,Dorzolamide HCl |
Carbonic Anhydrase
|
|
Dorzolamide hydrochloride (MK507 hydrochloride) is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of carbon dioxide and water ... |
|
T0037 |
Halazone
|
Cloritines,Pantocid,Halazon |
Sodium Channel
,
Antibacterial
,
Antibiotic
,
Carbonic Anhydrase
|
|
Halazone (Pantocid) is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water. |
